An idea of re-discovery of anomie is argued for basing on an assumption, thatmodern world is changing its contents and character under impact of growing mobility andcomplex social & cultural dynamics and a complex society in the making. Social realities arescrutinized contributing to assertion of an end of normative definiteness. Category of ‘normalanomie’ is proposed understood as a wider aggregate of vulnerabilities for society in the formof side-effects of innovative and rational-pragmatic activity of Man. To analyze them, an inte-gral theoretic methodological tool-set is demanded, which is based on a synthesis of social,natural sciences and humanities.