Interdisciplinary interactions of sociology with natural sciences are discussed focusing on the necessity to co-relate sociology’s mathematization to its ontologization in investigating social problems. Mostly, such interaction is limited to exchange of empiric methods. In author’s opinion, close interaction on the values basis is equally important. This is a situation, where sociology acts as adaptor of methodicval meeans for social scuences and hyumanities. Author argues that sociology has yet to play importanty role in both natural and social sciences and humanities. As for accentuating of co-relations of mathematization with “ontologization”, it is, so author, fundamental for effectiveness of interdisciplinary interactions. To sum up, author pleads for interactions of sociology with other academic branches in the axiological perspective.